Joseph Amos MD

Complex Regional Pain Syndrome

What is Complex Regional Pain Syndrome (CRPS)?

Complex Regional Pain Syndrome (CRPS) a chronic pain condition that typically affects a limb (arm, leg, hand, or foot) triggered by trauma or surgery, leading to dysregulated sympathetic nerve activity.

What causes Complex Regional Pain Syndrome (CRPS)?

While the exact cause of CRPS is not fully understood, it involves:

  • Nervous system dysfunction, especially of the central and peripheral nervous systems
  • Abnormal inflammatory response after an injury
  • Possible role of the immune system or genetic susceptibility

What do patients commonly experience?

Severe burning or throbbing pain in a limb, along with swelling, color changes, temperature changes, and skin sensitivity.

How is it diagnosed?

The first step to diagnose complex regional pain syndrome is to perform a thorough physical examination and carefully consider your medical and family history.

How is it treated?

Some of the treatments for Complex Regional Pain Syndrome (CRPS) include:

  • Physical therapy
  • Sympathetic nerve blocks
  • Neuropathic medications
  • Spinal cord stimulation
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